Scantibodies Contract Monoclonal Antibody Production

INTRODUCTION

The existence of heterophilic antibodies and their potential for causing interference in immunoassays has been known for many years.

The increasing use of the susceptible 2-site immunometric (“sandwich”) assay format has led to growing concern over the problem, and because of this Scantibodies Laboratory has developed a unique heterophilic blocking reagent (HBR) that minimizes the occurrence of heterophilic antibody interference.

IN THIS BRIEF…

–  Qualification Test for the Application of HBR
–  Heterophilic Antibody Interference – What is It?
–  The Unique Aspects of HBR over Conventional Blocking Methods
–  Heterophilic Interference – What is Known?
–  Heterophilic Antibodies – Sources
–  Heterophilic Interference – How is it Detected?
–  What is the Difference Between Heterophilic Antibody and HAMA?
–  What is a Blocking Reagent?
–  Characteristics of an Ideal Heterophilic Blocking Reagent
–  The Scantibodies Heterophilic Blocking Reagent (HBR)
–  Performance Characteristics
–  False Positive Identification
–  Availability

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Scantibodies Laboratory, Inc.

9336 Abraham Way
Santee, CA 92071 USA

Tel: 1-619-258-9300
Fax: 1-619-258-9366

cs@scantibodies.com

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