Scantibodies Contract Monoclonal Antibody Production
The existence of heterophilic antibodies and their potential for causing interference in immunoassays has been known for many years.
The increasing use of the susceptible 2-site immunometric (“sandwich”) assay format has led to growing concern over the problem, and because of this Scantibodies Laboratory has developed a unique heterophilic blocking reagent (HBR) that minimizes the occurrence of heterophilic antibody interference.
IN THIS BRIEF…
– Qualification Test for the Application of HBR
– Heterophilic Antibody Interference – What is It?
– The Unique Aspects of HBR over Conventional Blocking Methods
– Heterophilic Interference – What is Known?
– Heterophilic Antibodies – Sources
– Heterophilic Interference – How is it Detected?
– What is the Difference Between Heterophilic Antibody and HAMA?
– What is a Blocking Reagent?
– Characteristics of an Ideal Heterophilic Blocking Reagent
– The Scantibodies Heterophilic Blocking Reagent (HBR)
– Performance Characteristics
– False Positive Identification