A Purification Scientist is a professional who specializes in the separation, isolation and purification of compounds, such as antibodies, proteins, peptides and other biomolecules. The role of a Protein Purification Scientist is to develop and optimize methods for the purification of these biomolecules, which can then be used for a wide range of applications, including immunoassays, research, and biotechnology. Must possess strong problem-solving skills and the ability to think critically. They must be able to work independently and as part of a team, and have excellent communication and interpersonal skills. The field of purification science is constantly evolving, so staying current with new technologies and advances in the field is essential.
- Design and conduct experiments to optimize purification processes for antibodies, proteins, biological and biochemical products used in small and large scale manufacturing.
- Develop and validate analytical methods for characterization and quantitation of purified products.
- Troubleshoot and optimize purification processes and methods.
- Review processes to improve yields, reduce cost and produce consistent product.
- Write and review technical reports, protocols, and SOPs.
- Provide technical support to other teams and departments.
- Maintain detailed laboratory records and data.
- Adhere to GMP and ISO regulations.
- Industry experience in the purification of monoclonal and polyclonal antibodies and proteins.
- Experience with downstream processing for monoclonal and polyclonal antibodies and other biologics.
- Familiarity with cGMPs and ISO regulatory requirements for biopharmaceutical production.
- Strong experience with protein purification techniques, including column chromatography, Ultrafiltration, Ammonium Sulfate Precipitation, DEAE, Protein A, G, A/G, L, MabSelect, Agarose Resins, Affinity Chromatography, Small and Process-Scale Column Packing, Ligand Attachment Chemistry, Dialysis, Lyophilization, Buffer preparation, conjugating antibodies for ELISA, Chemiluminescent,, Lateral Flow immunoassays
- Hybridoma, Cell Culture and Mab production and purification.
- Experience with analytical techniques, including HPLC, UV-Vis spectroscopy, SDS-PAGE, BioCore (instrumentation by Cytiva to characterize the binding characteristics of antibodies to its target), Electrophoresis.
- Excellent written and verbal communication skills.
- Strong problem-solving and critical thinking skills.
- Ability to work independently and as part of a team.
- Regular, reliable and predictable attendance.
Requirements
- Minimum 5 years hands on, bench experience in Protein Purification, Analysis, and Processing Monoclonal and Polyclonal Antibodies
- This is a hands on, laboratory bench position, preparation of columns, purifications, testing, writing SOP’s and producing products
- Bi-lingual speaking, reading and writing Spanish is desired.
- Must have a valid passport.
- In addition to Santee the position requires working in Mexico and the Ramona Ranch.
- Occasional Domestic and International Travel to Customers, Trade Shows, etc.
We offer a comprehensive benefits package to include paid sick, vacation, medical, dental, vision, life insurance and 401(k).
Email your resume to: hr@scantibodies.com
Scantibodies Laboratory, Inc. is located at:
10946 Woodside Avenue North, Santee, CA 92071
